Questions about Terms of Use. Please review our privacy policy. View secure login page. Share your thoughts with other customers. This article has been cited by other articles in PMC. The pathological mechanism of pancreatic injury with DBTC is related to its direct toxic effect on the pancreas and its necrotic effect on the bile duct epithelium, which induces duct obstruction.

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L-arginine is an essential amino acid that has been used to induce severe necrotizing acute pancreatitis in rats.

Vector Genbank File pRosa In contrast to acute pancreatitis, chronic pancreatitis is characterized by irreversible tissue damage such as acinar cell atrophy and pancreatic fibrosis that results in exocrine and endocrine insufficiency.

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Acute pancreatitis and chronic pancreatitis are inflammatory disorders with diverse etiologies. Terms of Use General Terms and Conditions. ECFP expression in pancreatic beta-cells is evident from embryonic day E Creative Data Solutions CDS is a Vanderbilt Shared Resource and has extensive experience cerukian providing effective and robust solutions to challenges pertaining to research data using modern informatics and bioinformatics approaches.


Please check genotypes which will be recovered. Pancreatic stellate cells are activated by proinflammatory cytokines: Payment for services, products, shipping containers, and shipping costs that are rendered are expected within the payment terms indicated on the invoice or stated by contract. Share your thoughts with other customers.

Experimental Models of Pancreatitis

This model is highly reproducible and economical since it utilizes rats or mice. Immunohistochemistry shows the expression of fibronectin and collagen types I and III. This mouse will facilitate studies of retinoic acid signaling in an intact animal. There was a problem filtering reviews right now. MIP-CFP These transgenic mice express the Cerulean variant of Enhanced Cyan Fluorescent Protein under the control of mouse insulin 1 promoter, and fluorescent protein expression is observed in pancreatic beta-cells.

Krt17keratin Research Areas By Genotype This mouse can be used to support research in many areas including: We cannot guarantee the reproductive success of mice shipped to your facility. Sabrent Mini Travel 2.

Experimental Models of Pancreatitis

Author information Article notes Copyright and License information Disclaimer. Atrophy, the transdifferentiation of acinar units to duct-like tubular complexes, and dilatation of the intra-acinar lumen also developed. Cryorecovery to establish a Dedicated Supply for greater quantities of mice. Terms are granted by mosue review and stated on the customer invoice s and account statement.


Base Price Starting at: This mutant mouse strain may be useful in studies of diabetes and pancreatic beta islet cell biology.

Payment for services, products, shipping containers, and shipping costs that are rendered are expected within the payment terms indicated on the invoice or stated by contract.

– STOCK Tg(Ins1-Cerulean)24Hara/J

mohse Wireless Mouse, Patuoxun 2. The Donating Investigator reports that homozygotes are viable and fertile, but has not confirmed homozygosity. Histological examination reveals interlobular and intralobular fibroses in the form of nodular pancreatitis at 2 weeks after the induction of PDH. This sequence was followed by a frt-flanked neomycin neo resistance cassette.